SUBCUTANEOUS (SC) KETAMINE THERAPY: A NEW OPTION & APPROACH TO TREATMENT-RESISTANT DEPRESSION

What is Subcutaneous (SC) Ketamine Therapy?

Subcutaneous ketamine therapy represents an innovative advancement in ketamine treatment, and offers patients a more precise and comfortable approach to ketamine-assisted psychotherapy. Unlike traditional IV ketamine, IM ketamine, or nasal spray methods, subcutaneous administration delivers ketamine through a small injection under the skin, providing consistent therapeutic effects with enhanced patient comfort.

Our ketamine therapy practice serves adults and teens in Chapel Hill, NC, Durham, NC, and Raleigh, NC. We’re proud to offer this cutting-edge treatment for adults and teens struggling with treatment-resistant mental health conditions.

How Subcutaneous Ketamine Differs from Other Methods

Subcutaneous vs. IV Ketamine:

  • More comfortable administration — smaller needle, without needles in veins

  • Consistent, prolonged absorption and therapeutic effects

  • Reduced medical monitoring requirements

  • Lower cost than IV ketamine treatments

Subcutaneous vs. Nasal Ketamine (Spravato) or compounded intranasal ketamine:

  • Better bioavailability and predictable effects

  • No taste or nasal irritation (seriously… no yucky taste, no dripping, no swallowing)

  • More precise dosing control

  • Enhanced therapeutic experience leads to more time in-session for psychotherapy & integration

Conditions Treated with Ketamine Therapy in our Chapel Hill / Durham Office

Our subcutaneous ketamine-assisted psychotherapy effectively treats:

Treatment-Resistant Depression

Many patients have found relief through ketamine therapy when traditional antidepressants haven't worked. Research shows that up to 70% of patients with treatment-resistant depression respond positively to ketamine treatment.

Anxiety Disorders

  • Generalized anxiety disorder

  • Social anxiety

  • Panic disorder

  • PTSD-related anxiety

Post-Traumatic Stress Disorder (PTSD)

Ketamine therapy creates a unique therapeutic window for processing traumatic experiences with reduced emotional overwhelm, making it highly effective for PTSD treatment.

Chronic Pain with Depression

The dual action of ketamine addresses both chronic pain and associated depression, offering comprehensive relief for patients dealing with both conditions.

The Subcutaneous Ketamine Treatment Process

Initial Consultation: During your first visit to our Chapel Hill location, we conduct a comprehensive evaluation to determine if subcutaneous ketamine therapy is right for you. This includes reviewing your medical history, current medications, and treatment goals.

Treatment Sessions:

  • Sessions typically last 2-3 hours

  • Subcutaneous ketamine injection administered in a comfortable, medically supervised, home-like setting

  • Psychotherapy integration during the experience

  • Recovery and integration time before discharge

Follow-up Care: We provide ongoing support and integration sessions to help you maximize the benefits of your ketamine therapy experience.

Benefits of Subcutaneous Ketamine Therapy

Rapid Relief: Unlike traditional antidepressants that take weeks to work, ketamine therapy can provide relief within hours or days of treatment.

Neuroplasticity: Ketamine promotes the growth of new neural connections, literally helping your brain form healthier thought patterns.

Reduced Side Effects: Subcutaneous administration typically produces fewer side effects than other ketamine delivery methods.

Enhanced Therapy: The altered state of consciousness allows for deeper therapeutic work and breakthrough insights.

Why Choose Our Practice for Ketamine Therapy?

Convenient Triangle Area Locations: With offices conveniently located in Chapel Hill, NC and close to I-40, we make ketamine therapy accessible to patients throughout the Triangle. Transportation a problem? We also do home visits! Ask us to learn more about how we can come to you.

Specialized Expertise: Our team specializes specifically in ketamine-assisted psychotherapy, combining medical expertise with psychological insight for optimal outcomes.

Personalized Treatment: Every treatment plan is customized to your specific needs, history, and therapeutic goals.

Comprehensive Care: We provide full support from initial consultation through ongoing integration and follow-up care.

Is Subcutaneous Ketamine Therapy Right for You?

Good candidates for ketamine therapy typically include:

  • Adults and teens with treatment-resistant depression

  • Patients who haven't responded to multiple antidepressant trials

  • Individuals with PTSD or complex trauma

  • Those seeking rapid relief from severe depression or suicidal ideation

  • Patients interested in combining medication with psychotherapy

  • Individuals who are wary of getting ketamine in an unsupported environment (minimal to no therapy), or from a provider who hasn’t completed any certifications or training specifically in ketamine/psychedelic medicine

Getting Started with Ketamine Therapy

Step 1: Initial Consultation Contact us (sarah@cantoteampractice) to schedule your comprehensive evaluation.

Step 2: Treatment Planning We'll work with you to develop a personalized ketamine therapy treatment plan. We’ll discuss all routes of administration offered in our office: oral, intranasal, subcutaneous, and intramuscular - to decide which route is best for you and your needs

Step 3: Begin Treatment Start your ketamine-assisted psychotherapy sessions in our comfortable, supportive environment.

Research and Safety

Ketamine therapy is backed by extensive research demonstrating its safety and efficacy for treatment-resistant depression. The subcutaneous route we use has been shown to provide:

  • Consistent therapeutic blood levels

  • Reduced risk of complications compared to IV administration

  • High patient satisfaction and comfort

  • Effective symptom relief with minimal side effects

Insurance and Cost

While ketamine therapy is often not covered by insurance, we work with patients to make treatment accessible. We accept Health Savings Account (HSA) and Flexible Spending Account (FSA) payments, and we are proud to offer the lowest rates for comprehensive ketamine service in the Triangle.

Contact Our Chapel Hill Ketamine Therapy Practice

Ready to explore whether subcutaneous ketamine therapy could help you find relief from treatment-resistant depression, anxiety, or trauma? Our experienced team is here to answer your questions and help you determine if this innovative treatment is right for you.

Chapel Hill Location: 1829 E Franklin Street, Bldg 100-A Chapel Hill NC 27514; sarah@cantoteampractice.com

Don't let treatment-resistant depression control your life. Contact us today to learn more about subcutaneous ketamine-assisted psychotherapy and take the first step in your healing journey.

Serving patients throughout the Research Triangle area, our ketamine therapy practice offers subcutaneous ketamine-assisted psychotherapy for adults and teens struggling with treatment-resistant mental health conditions. Located in Chapel Hill, NC.

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WHAT TO EXPECT: SIDE EFFECTS OF KETAMINE THERAPY